Exacerbation of oxaliplatin neurosensory toxicity following surgery

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Exacerbation of oxaliplatin neurosensory toxicity following surgery.

Combination of chemotherapy and surgical resection of metastases is the most promising strategy to improve the fraction of long-term survivors and cured patients in metastatic colorectal cancer. We reproducibly observed evidence of exacerbation of the oxaliplatin-induced neurosensory toxicity following surgery. Total, protein-bound and intra-erythrocytic concentrations of oxaliplatin were measu...

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ژورنال

عنوان ژورنال: Annals of Oncology

سال: 2002

ISSN: 0923-7534

DOI: 10.1093/annonc/mdf254