Evolving Ideas about Cyclins

Evolving Ideas about Cyclins

instance, is associated primarily with activation of S James M. Roberts Division of Basic Sciences phase whereas CDK1 primarily with mitosis. However, assays using defined peptides reveal only subtle differFred Hutchinson Cancer Research Center and Howard Hughes Medical Institute ences in substrate preference between CDK1 and CDK2 (Holmes and Solomon, 1996), and there is no compelling 1100 Fair...

Evolving ideas in primary care.

The other day I saw a new mom with a 5-week-old baby who spent a good part of his day crying. The mom had done the things moms with babies who cry a lot often do: she had blamed something in her breast milk and stopped breastfeeding, then she had started working her way through the various infant formulas in the grocery store; still her baby would not stop crying. “He looks like he’s in pain. H...

Some Ideas About Colour

Emerging Ideas About Categories

The study of human categorization is contentious because it matters. How we understand the processes that give rise to categories is at the very core of how we understand human cognition. Over the past several decades, there has been growing concern that the assumptions that define and distinguish competing theories may notbe quite right. These assumptions are based on the traditional metaphor ...

Human systems as linguistic systems: preliminary and evolving ideas about the implications for clinical theory.

From our earliest practice of family therapy at medical schools, private family therapy institutes, and public agencies, our work with difficult populations that do not respond to current treatment technologies has reminded us of the inadequacies of our theoretical descriptions and the limitations of our expertise. This work has influenced our current, evolving clinical theory as we move from t...