Evolutionary dynamics of incubation periods

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Evolutionary dynamics of incubation periods

The incubation period for typhoid, polio, measles, leukemia and many other diseases follows a right-skewed, approximately lognormal distribution. Although this pattern was discovered more than sixty years ago, it remains an open question to explain its ubiquity. Here, we propose an explanation based on evolutionary dynamics on graphs. For simple models of a mutant or pathogen invading a network...

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The Incubation Periods of Dengue Viruses

Dengue viruses are major contributors to illness and death globally. Here we analyze the extrinsic and intrinsic incubation periods (EIP and IIP), in the mosquito and human, respectively. We identified 146 EIP observations from 8 studies and 204 IIP observations from 35 studies. These data were fitted with censored Bayesian time-to-event models. The best-fitting temperature-dependent EIP model ...

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Multiple Contact Dates and SARS Incubation Periods

Many severe acute respiratory syndrome (SARS) patients have multiple possible incubation periods due to multiple contact dates. Multiple contact dates cannot be used in standard statistical analytic techniques, however. I present a simple spreadsheet-based method that uses multiple contact dates to calculate the possible incubation periods of SARS.

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The influence of incubation periods on photosynthesis–irradiance curves

In phytoplankton primary production studies, samples for the determination of photosynthesis versus irradiance relationship (P– I) are usually incubated at several irradiance levels during a fixed time period, commonly 2–4 h. However, it is not clear if the use of this fixed incubation time is appropriate to study the P– I relationship in any given ecosystem. The aim of this work was to study t...

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Incubation periods of viral gastroenteritis: a systematic review

BACKGROUND Accurate knowledge of incubation period is important to investigate and to control infectious diseases and their transmission, however statements of incubation period in the literature are often uncited, inconsistent, and/or not evidence based. METHODS In a systematic review of the literature on five enteric viruses of public health importance, we found 256 articles with incubation...

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ژورنال

عنوان ژورنال: eLife

سال: 2017

ISSN: 2050-084X

DOI: 10.7554/elife.30212