EVOLUTION: Stripped Down to the Bare Essentials

The bare essentials: coma.

The bare essentials: muscle disease.

Correspondence to: Professor M G Hanna, MRC Centre for Neuromuscular Diseases, Institute of Neurology and National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK; [email protected] Muscle diseases impair mobility and frequently have cardiorespiratory complications. Their age of onset is extremely wide; patients may die young, or there may be lifelong motor disabil...

Epidermal differentiation: the bare essentials

N the past ten years, there have been a number of major scientific discoveries in the field of epidermal differentiation. We owe many of these findings to the development of model tissue culture systems, and to technological advances in molecular biology. In this article, I will review some important aspects of the biology of terminal differentiation in vivo and in vitro, and highlight the rece...

The bare essentials: Functional symptoms in neurology.

Correspondence to: Dr J Stone, Consultant Neurologist and Honorary Senior Lecturer in Neurology, Department of Clinical Neurosciences, Western General Hospital, Edinburgh EH4 2XU, UK; [email protected] IS IT YOUR JOB AS A NEUROLOGIST TO DEAL WITH THIS PROBLEM? If you find people with ‘‘neurological symptoms but no disease’’ tiresome and not really what you came in to the specialty for, then yo...

Evaluating neurological outcome measures: the bare essentials.

Editorial Evaluating neurological outcome measures: the bare essentials Chronic impairment is a common consequence of neuro-logical disease. Many of these disorders affect the younger age group and are often progressive over many decades. Measurement of health related outcomes such as disability, handicap, and quality of life are therefore important in the evaluation of therapeutic efficacy. To...