Evalution of Tp-E Interval on Electrocardiography Recordings in Elderly Hemodialysis Patients And Its Associations With Electrolyte Imbalances

Aim: Sudden cardiac death (SCD) due to arrhythmias is a major cause of in elderly patients on hemodialysis (HD). It has been found that prolonged Tp-e interval (Tpe) electrocardiography (ECG) and increased Tpe/QTc ratio are strongly associated with SCD. In this study, we aimed inves¬tigate the effects changes serum electrolyte levels pre- post-HD ECG parameters, particularly Tpe. Methods: The study included 160 HD (with no disease or medication known affect QT interval) 80 age- sex-matched controls normal kidney functions. All participants were aged 55 years older. Pre- values re¬cordings obtained. heart rate, QRS interval, QTc, Tpe, calculated. pre-HD data compared as well controls. Results: Tpe (p<0.001 for both comparisons) (p=0.024 p<0.001, respectively) significantly higher group than control group. each comparison). was longer hypocalcemia hy¬perphosphatemia normocalcemic normophosphatemic (p=0.04 data¬sets). ΔTpe correlated Δcalcium (r=-0.19, p=0.02) Δphosphorus (r=-0.23, p=0.004). Conclusion: HD, which before even more after HD. Hypocalcemia hyperphosphatemia may be among un¬derlying factors.