Evaluation of Traditional Medicines for Neurodegenerative Diseases UsingDrosophilaModels
نویسندگان
چکیده
منابع مشابه
Evaluation of Traditional Medicines for Neurodegenerative Diseases Using Drosophila Models
Drosophila is one of the oldest and most powerful genetic models and has led to novel insights into a variety of biological processes. Recently, Drosophila has emerged as a model system to study human diseases, including several important neurodegenerative diseases. Because of the genomic similarity between Drosophila and humans, Drosophila neurodegenerative disease models exhibit a variety of ...
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Ashwagandha (root of Withania somnifera) has been used for many purposes, it is mainly considered a tonic in traditional Ayurvedic medicine. This review focuses on the effects of compounds isolated from Ashwagandha on dementia models and on the spinal cord injury model. Our study demonstrated that the active constituents, withanolide A, withanoside IV, and withanoside VI, restored presynapses a...
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Neurodegenerative diseases (NDD), such as Alzheimer's disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS), are one of leading causes of death all over the world. Traditional medicine (TM), especially traditional Chinese medicine (TCM), usually having good clinical tolerability, is applied to treat NDD in China based on TCM or modern pharmacological theories. This iss...
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Herbal medicine has long been used to treat neural symptoms. Although the precise mechanisms of action of herbal drugs have yet to be determined, some of them have been shown to exert anti-inflammatory and/or anti-oxidant effects in a variety of peripheral systems. Now, as increasing evidence indicates that neuroglia-derived chronic inflammatory responses play a pathological role in the central...
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ژورنال
عنوان ژورنال: Evidence-Based Complementary and Alternative Medicine
سال: 2014
ISSN: 1741-427X,1741-4288
DOI: 10.1155/2014/967462