Evaluation of Some Lectins as Anti-protozoal Agents
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چکیده
منابع مشابه
Discovery and Evaluation of Thiazinoquinones as Anti-Protozoal Agents
Pure compound screening has identified the dioxothiazino-quinoline-quinone ascidian metabolite ascidiathiazone A (2) to be a moderate growth inhibitor of Trypanosoma brucei rhodesiense (IC₅₀ 3.1 μM) and Plasmodium falciparum (K1 dual drug resistant strain) (IC₅₀ 3.3 μM) while exhibiting low levels of cytotoxicity (L6, IC₅₀ 167 μM). A series of C-7 amide and Δ²(³) analogues were prepared that ex...
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ژورنال
عنوان ژورنال: Journal of Medical Sciences
سال: 2004
ISSN: 1682-4474
DOI: 10.3923/jms.2005.31.34