Evaluation of Pharmacodynamic Properties and Safety of Cinnamomum Zeylanicum (Ceylon Cinnamon) in Health Adults: Study Protocol for a Phase I Clinical Trial

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Evaluation of pharmacodynamic properties and safety of Cinnamomum zeylanicum (Ceylon cinnamon) in healthy adults: a phase I clinical trial

BACKGROUND Cinnamon is considered as a treatment for many ailments in native medicine. Evidence suggests that Cinnamomum zeylanicum (CZ) has anti-microbial, anti-parasitic, anti-oxidant, blood glucose lowering properties and beneficial cardiovascular effects. The present study aims to evaluate Pharmacodynamic properties and safety of CZ in healthy adults using a Phase I Clinical Trial. METHOD...

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Evaluation of Pharmacodynamic Properties and Safety of Cinnamomum Zeylanicum (Ceylon Cinnamon) in Health Adults: Study Protocol for a Phase I Clinical Trial

Submit Manuscript | http://medcraveonline.com Abbreviations: ALD: Alcoholic Liver Disease; FBG: Fasting Blood Glucose; LDL: Low Density Lipoprotein; HDL: High Density Lipoprotein; VAS: Visual Analog Scales; FBC: Full Blood Count; SBP: Systolic Blood Pressure; DBP: Diastolic Blood Pressure; BMI: Body Mass Index; WC: Waist Circumference; HC: Hip Circumference; WHR: Waist Hip Ratio; FFQ: Food Freq...

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Medicinal properties of ‘true’ cinnamon (Cinnamomum zeylanicum): a systematic review

BACKGROUND In traditional medicine Cinnamon is considered a remedy for respiratory, digestive and gynaecological ailments. In-vitro and in-vivo studies from different parts of the world have demonstrated numerous beneficial medicinal effects of Cinnamomum zeylanicum (CZ). This paper aims to systematically review the scientific literature and provide a comprehensive summary on the potential medi...

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Cinnamomum zeylanicum (Ceylon cinnamon) as a potential pharmaceutical agent for type-2 diabetes mellitus: study protocol for a randomized controlled trial

BACKGROUND Previous studies have explored the anti-diabetic effects of Cinnamomum cassia extract in vivo and in vitro. However, there are no studies at present exploring the effects of the indigenous species of Sri Lankan cinnamon (Cinnamomum zeylanicum) in patients with diabetes mellitus. The present study aims to evaluate the potential effects of Cinnamomum zeylanicum extract as a pharmaceuti...

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Effects of Cinnamomum zeylanicum (Ceylon cinnamon) on blood glucose and lipids in a diabetic and healthy rat model

OBJECTIVES To evaluate short- and long-term effects of Cinnamomum zeylanicum on food consumption, body weight, glycemic control, and lipids in healthy and diabetes-induced rats. MATERIALS AND METHODS The study was conducted in two phases (Phase I and Phase II), using Sprague-Dawley rats in four groups. Phase I evaluated acute effects on fasting blood glucose (FBG) (Groups 1 and 2) and on post...

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ژورنال

عنوان ژورنال: MOJ Bioequivalence & Bioavailability

سال: 2017

ISSN: 2573-2951

DOI: 10.15406/mojbb.2017.03.00028