Evaluation of metal-mediated DNA binding of benzoxazole ligands by electrospray ionization mass spectrometry
نویسندگان
چکیده
منابع مشابه
Evaluation of metal-mediated DNA binding of benzoxazole ligands by electrospray ionization mass spectrometry.
The binding of a series of benzoxazole analogs with different amide- and ester-linked side chains to duplex DNA in the absence and presence of divalent metal cations is examined. All ligands were found to form complexes with Ni2+, Cu2+, and Zn2+, with 2:1 ligand/metal cation binding stoichiometries dominating for ligands containing shorter side chains (2, 6, 7, and 8), while 1:1 complexes were ...
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ژورنال
عنوان ژورنال: Journal of the American Society for Mass Spectrometry
سال: 2008
ISSN: 1044-0305,1879-1123
DOI: 10.1016/j.jasms.2007.05.009