Evaluation of Lipid Profile and Liver Function After Administration of Scenedesmus dimorphus in Obese Mice
نویسندگان
چکیده
Obesity is a major public health problem in developing countries and significant risk factor for metabolic disorders. Microalgae Scenedesmus dimorphus (S. dimorphus) contains bioactive compounds such as pigment function antioxidants, omega-3 omega-6 PUFAs have potential nutraceuticals. The study aimed to evaluate the lipid profile liver after administration of S. obese mice. research design uses mice which are divided into 6 groups; Group 1 (G1) normal control, G2 control Obesity, G3 treatment with Orlistat, G4 (0.25mg/g BW), G5 (0.5 mg/g BW) G6 (0.75 each group consisted 5 21 days observation time. parameters observed were Based on results study, effective dose treating obesity 0.75 (BW) can reduce cholesterol, triglycerides, LDL levels, respectively 67.7 mg/dl, 49.2 10 , 2 increased HDL, 68.32 mg/dl compared (G2), 108.7 139.1 20.6 HDL 60, 28 this also improving blood pressure by reducing AST ALT 15.6 U/L 18.8 U/L, respectively, 26.6 29,7 U/L. it be concluded that useful anti-obesity (Mus musculus).
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ژورنال
عنوان ژورنال: Jurnal riset kimia
سال: 2022
ISSN: ['1978-628X', '2476-8960']
DOI: https://doi.org/10.25077/jrk.v13i2.503