Evaluation of Gene Expression in Peripheral Blood Cells as a Potential Biomarker for Enzootic Bovine Leukosis
نویسندگان
چکیده
منابع مشابه
Evaluation of gene expression in peripheral blood cells as a potential biomarker for enzootic bovine leukosis.
Expression of six selective genes in peripheral blood cells was evaluated as diagnostic biomarkers for enzootic bovine leukosis (EBL) by using 10 EBL and 15 clinically healthy cattle. The clinically healthy cattle generally showed lower gene expression levels. Although wide variations of gene expression were found in some clinical cases of EBL, 4 and 5 among 10 EBL cattle showed higher expressi...
متن کاملEnzootic Bovine Leukosis
Bovine Leukemia Virus (BLV) is the etiologic agent of Enzootic Bovine Leukosis, a retrovirus exogenous to the bovine species. Once infected, there is no detectable viraemia but instead there is a strong and persistent immunological response to BLV structural proteins, essentially the gp51 envelope glycoprotein and the mayor core protein p24. We describe the test procedure of an indirect ELISA (...
متن کاملEnzootic Bovine Leukosis
Both EBL and SBL occur in southern Africa and in the Southern African context it will therefore be very important to accurately differentiate between EBL and SBL. The epidemiology, direct and indirect economic impact, diagnosis and most importantly control and eradication of EBL is markedly different to that of SBL. Globally EBL infection may also place severe restrictions on the import and exp...
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Infection of bovines with bovine leukaemia virus (BLV) manifests itself in either of two ways: 30-70% of carriers develop persistent lymphocytosis (PL), with the viral genome integrated at a large number of different sites in the DNA of the affected B-lymphocytes, without causing any chromosomal abnormalities. Only 0,1-10% of carriers develop lymphoid tumours, which also consist of B-lymphocyte...
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Mesenchymal stem cells (MSCs) provide a novel option in cellular therapy and tissue engineering. Recent studies indicated that it is possible to obtain MSCs from peripheral blood by attachment ability to plastic surface. To evaluate adherent cells derived from peripheral blood, their expression profile and surface markers were investigated. The results of RT-PCR indicated that these cells expre...
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ژورنال
عنوان ژورنال: Journal of Veterinary Medical Science
سال: 2013
ISSN: 0916-7250,1347-7439
DOI: 10.1292/jvms.13-0109