Evaluation of BMMSCs-EPCs sheets for repairing alveolar bone defects in ovariectomized rats
نویسندگان
چکیده
منابع مشابه
Bone Deficit in Ovariectomized Rats
This study investigates the proliferative and osteogenic role of marrow stromal/osteoprogenitor cells in the development of the cortical bone deficit in ovariectomized (OVX) female rats. In vitro, clonal growth of marrow stromal cells from OVX rats was significantly impaired (vs. sham-operated controls). Yet in vivo, cells from sham-operated and OVX rats had equal osteogenic potential in severa...
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The aim of this study was to evaluate the osteoprotective effect of aqueous Rhizoma Dioscoreae extract (RDE) on the alveolar bone of rats with ovariectomy-induced bone loss. Female Wistar rats underwent either ovariectomy or sham operation (SHAM). The ovariectomized (OVX) rats were treated with vehicle (OVX), estradiol valerate (EV), or RDE. After treatments, the bone mineral density (BMD) and ...
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INTRODUCTION: The effects of gravity on bone metabolism are unclear. Most studies in humans and laboratory animal models have revealed that exposure to microgravity during spaceflight leads to bone loss, but the details of its mechanism are still unclear. On the other hand, some studies have reported the effects of hypergravity on mature skeleton, but the details of the effect of hypergravity o...
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Vascularized periosteal flaps are used for complex cases if the reconstruction of large bone defects is necessary in modern trauma and orthopedic surgery. In this study, we combined this surgical procedure with β‑TCP scaffold and mesenchymal stem cells (MSCs) + endothelial progenitor cells (EPCs) as a tissue engineering approach to obtain optimum conditions for bone healing in rats. A critical ...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2017
ISSN: 2045-2322
DOI: 10.1038/s41598-017-16404-3