EVALUATION OF ANTI-OXYTOCIC ACTIVITY OF ASPARAGUS RACEMOSUS JINISH JOSE DEPARTMENT OF PHARMACOLOGY

Objective: The objective of the study was to evaluate anti-oxytocic activity ethanolic extract Asparagus racemosus root.
 Methods: Ethanolic A. root taken by Soxhlet extraction method. Wistar strain albino non-pregnant female rats weight 200–300 g were pre-treated with estrogen and sacrificed take their uterus. tissue then mounted in an organ bath containing de Jalon’s solution. response various doses oxytocin alone on adding increasing alcoholic extracts along dose which produces sub-maximal contraction recorded a smoked drum.
 Results: Extract up 40 mg when given 0.1 unit produced graded increase contractions rat From 80 onward blockade occurred complete at 200 mg. On removal thorough washing, it seen that again able produce uterus tissue.
 Conclusion: had demonstrated good property.