Evaluation of anaesthesia with xylazine-ketamine and xylazine-fentanyl-ketamine in rabbits: A comparative study

Clinical and serum biochemical markers were utilized to assess the clinical efficacy of routinely used preanaesthetics induction agents in rabbits. Eight healthy rabbits (3.0-3.5kg) either sex randomly assigned one two groups: XK (Xylazine-ketamine) or XFK (Xylazine–fentanyl–ketamine). Intramuscular injections xylazine (5 mg/kg), ketamine (35 fentanyl (0.02 mg/kg) given parameters (rectal temperature, heart rate, respiratory rate), as well reflexes (righting reflex, palpebral pedal reflex), measured before after anaesthetic injection at 10, 20, 30, 40, 50, 60, 70, 80, 90, 100 minutes. Blood samples also taken anaesthesia 30 minutes following induction. An autoanalyzer was examine parameters. In group, we observed that rectal temperature increased considerably (P