Evaluation of a chitosan-polyethylene glycol paste as a local antibiotic delivery device

Evaluation of a chitosan-polyethylene glycol paste as a local antibiotic delivery device

AIM To investigate the efficacy of a chitosan/polyethylene glycol blended paste as a local antibiotic delivery device, particularly in musculoskeletal wounds. METHODS Acidic (A) chitosan sponges and neutralized (N) chitosan/polyethylene glycol (PEG) blended sponges were combined in ratios of 3A:2N, 1A:1N, and 2A:3N; then hydrated with phosphate buffered saline to form a chitosan/PEG paste (CP...

vancomycin loaded chitosan beads as a drug delivery system for local antibiotic delivery in some infections

Evaluation of chitosan gel as antibiotic and photosensitizer delivery.

This work suggests the use of chitosan gel imbued with the photosensitizer Photogem and with the antibiotic Tetraclin as a possible drug delivery system. The results reveal a decrease in the photosensitizer level of toxicity. Besides, the interaction between Photogem and chitosan gel causes a red shift in the photosensitizer spectrum, increasing its absorption in the therapeutic window (600-700...

the significance of conjunction as a cohesive device in teaching writing

the research questions were as follows: 1. is there any relationship between the students concious awareness of the form and implications of the conjuncations and their improvement in using appropriate conjunctions? 2. does students knowledge of the from and the implications of the conjunctions help them to produce more coherent writings. 3. does a comparison between english conjunctions and th...

Polyethylene glycol as a cause of anaphylaxis

BACKGROUND Polyethylene glycols (PEGs) or macrogols are polyether compounds and are widely used as additives in pharmaceuticals, cosmetics, and food. CASE REPORT We report on a Caucasian patient experiencing recurrent severe allergic reactions to several drugs. An extensive diagnostic workup including skin prick tests, intradermal tests (IDT) and a double-blind oral challenge was performed to...