Evaluation and optimization of clustering in gene expression data analysis
نویسندگان
چکیده
منابع مشابه
Evaluation and optimization of clustering in gene expression data analysis
MOTIVATION A measurement of cluster quality is needed to choose potential clusters of genes that contain biologically relevant patterns of gene expression. This is strongly desirable when a large number of gene expression profiles have to be analyzed and proper clusters of genes need to be identified for further analysis, such as the search for meaningful patterns, identification of gene functi...
متن کاملEvaluation and optimization of clustering in gene expression data analysis Journal of Bioinformatics 1 Evaluation and optimization of clustering in gene expression data analysis
Motivation: A measurement of cluster quality is needed to choose potential clusters of genes that contain biologically relevant patterns of gene expressions. This is strongly desirable when large number of gene expression profiles have to be analyzed and proper clusters of genes need to be identified for further analysis, such as the search for meaningful patterns, identification of gene functi...
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15 صفحه اولEvaluation of Clustering Based on Preprocessing in Gene Expression Data
Microarrays have become the effective, broadly used tools in biological and medical research to address a wide range of problems, including classification of disease subtypes and tumors. Many statistical methods are available for analyzing and systematizing these complex data into meaningful information, and one of the main goals in analyzing gene expression data is the detection of samples or ...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2004
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/bth124