Evaluate the Efficiency of A60 Protein from BCG Strain of Mycobacterium Bovis as a Diagnostic Antigen
نویسندگان
چکیده
منابع مشابه
Immunological analysis of the components of the antigen complex A60 of Mycobacterium bovis BCG.
The antigen complex of A60 of Mycobacterium bovis BCG was analyzed by different immunological techniques to assess its relevance to tuberculosis and the involvement of its components in the immune reactions elicited in humans by tuberculous infection. A60 is composed of about 30 components, of which 8 were identified by available monoclonal antibodies (lipoarabinomannan, a glycolipid, and prote...
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Tuberculosis (TB) is a zoonotic infectious disease common to humans and animals which has been caused by a rod shaped, acid fast bacterium, called Mycobacterium bovis. The rapid and sensitive detection is a great challenge for TB diagnosis. The virulent strains of Mycobacterium tuberculosis complex (MTBC) have 16 different regions of difference (RD) in their genome which encode some important a...
متن کاملارزیابی کارایی پروتئین A60 باکتری مایکوباکتریوم بوویس سویه BCG به عنوان پادگن تشخیصی
Tuberculosis is the most common infectious diseases. Current diagnostic methods are either slow or lack enough sensivity or specificity. Several mycobacterial antigens are involved in the complex interaction with the immune system of the host. They can be helpful for mycobacteria diagnosis. Antigen 60 (A60) is thermostable antigen found in Mycobacterium bovis and Mycobacterium tuberculosis...
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The mechanism of action of isoniazid (INH) on Mycobacterium bovis strain BCG was studied. The rates of synthesis of deoxyribonucleic acid (DNA), ribonucleic acid (RNA), and protein after the addition of INH to growing cultures were followed by measuring the incorporation of (3)H-thymidine, (3)H-uridine, and (14)C-l-valine, respectively. After the addition of INH, the rate of DNA synthesis began...
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12 Affiliations: 13 14 Vandana Singh 15 Senior Project Fellow 16 Division of Microbiology 17 CSIR-Central Drug research Institute 18 Lucknow, 226031, INDIA, E. mail: [email protected] 19 20 Rajesh Kumar Biswas 21 Senior Research Fellow 22 Division of Microbiology 23 CSIR-Central Drug research Institute 24 Lucknow, 226031, INDIA, E. mail: [email protected] 25 26 27 28 29 Corresponden...
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ژورنال
عنوان ژورنال: Research on Animal Production
سال: 2017
ISSN: 2251-8622
DOI: 10.29252/rap.8.16.137