evaluate the drug resistance pattern in various antibiotics with biofilm-producing capability of Klebsiella pneumoniae

Aim: Objective of study was to evaluate the drug resistance pattern in various antibiotics with biofilm-producing capability Klebsiella pneumoniae. Methods: pneumoniae isolated for identification from total 83 OPD and IPD patients by analysing colony morphology, microscopic examination, performed biochemical testing. Antibiotics susceptibility Tests capacity done Kirby-Bauer disk diffusion method adherence quantitative assays. Chi-square test used P < 0.05 measured as statistically significant. Results: Out isolates, 47 (56.6%) were Biofilm Producer 36 (43.4%) non-biofilm producers tissue culture method, tube 62.7% 37.3% respectively. Among biofilm producer had most Resistant Ceftazidime (100%) & (61.0%), followed Ceftriaxone (56.0%) (95.7%) The association between antibiotic checked be significant aminoglycosides, fluoroquinolones, Cephalosporin’s, Imipenem, Meropenem, Amoxyclav, Piperacillin Tazobactam. No observed against Colistin Polymyxin B. Conclusion: strain different samples showed all broad-spectrum whereas there is no found narrow-spectrum drugs. This supports use infections.