Evaluate a Repeated Oral Dose Toxicity and Immunomodulating Activity of <TEX>$Pulsatilla$</TEX> <TEX>$koreana$</TEX> and <TEX>$Artemisiae$</TEX> <TEX>$annuae$</TEX> in Sprague-Dawley Rats
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چکیده
منابع مشابه
A 4-Week Repeated-Dose Oral Toxicity Study of Bojungikgi-Tang in Crl:CD Sprague Dawley Rats
Traditional herbal medicines have been used for centuries in Asian countries. However, recent studies have led to increasing concerns about the safety and toxicity of herbal prescriptions. Bojungikgi-tang (BJIGT), a herbal decoction, has been used in Korea to improve physical strength. To establish the safety information, BJIGT water extract was evaluated in a 4-week repeated-dose oral toxicity...
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OBJECTIVES Mountain ginseng pharmacopuncture (MGP) is a pharmacopuncture made by distilling extract from mountain cultivated ginseng or mountain wild ginseng. This pharmacopuncture is injected intravenously, which is a quick, lossless way of strongly tonifying Qi function. The present study was undertaken to evaluate a 4-week, repeated, intravenous injection, toxicity test of MGP in Sprague-Daw...
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OBJECTIVES Water-soluble carthami flos (WCF) is a new mixture of Carthami flos (CF) pharmacopuncture. We conducted a 4-week toxicity test of repeated intramuscular injections of WCF in Sprague-Dawley rats. METHODS Forty male and 40 female rats were divided into 4 groups of 10 male and 10 female SD rats: The control group received 0.5 mL/animal/day of normal saline whereas the three experiment...
متن کاملA Study on the Single-dose Oral Toxicity of Super Key in Sprague-Dawley Rats
OBJECTIVES This study was performed to analyze the single-dose oral toxicity of the super key (processed sulfur). METHODS All experiments were conducted at Medvill, an institution authorized to perform non-clinical studies, under the Good Laboratory Practice (GLP) regulations. In order to investigate the oral toxicity of super key We administered it orally to Sprague-Dawley (SD) rats. The SD ...
متن کاملA 4-week Repeated dose Oral Toxicity Study of Mecasin in Sprague-Dawley Rats to Determine the Appropriate Doses for a 13-week, Repeated Toxicity Test
OBJECTIVES In this study, we investigated the 4-week repeated-dose oral toxicity of gami-jakyak gamcho buja decoction (Mecasin) to develop safe treatments. METHODS In order to investigate the 4-week oral toxicity of Mecasin, we administered Mecasin orally to rats. Sprague-Dawley (SD) rats were divided into four groups of five male and five female animals per group: group 1 being the control g...
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ژورنال
عنوان ژورنال: Journal of Food Hygiene and Safety
سال: 2012
ISSN: 1229-1153
DOI: 10.13103/jfhs.2012.27.1.096