Ethylene glycol poisoning treated using combination of ethanol and haemodialysis therapy instead of fomepizole: a case report
نویسندگان
چکیده
We report a case of ethylene glycol poisoning in 70-year-old man with headache and dysarthria. Blood tests showed marked increase the anion gap (29.8 mOsm/kg) osmotic (14 mOsm/kg). The estimated blood concentration was 86.8 mg/dL. Ethanol administered he underwent haemodialysis for 7 cycles, which discontinued on day 12. Fomepizole, competes alcohol dehydrogenase, is an effective treatment poisoning. However, it usually prescribed within 24 h after poisoning, studies its use cases severe acute renal injury over time are limited. were able to obtain good results without using fomepizole. Conventional treatments such as may be more useful than fomepizole terms cost benefits patients addiction who have been taking drug long or advanced injury. Â
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Ethylene glycol is one of the most common toxic alcohol ingestions requiring hemodialysis for treatment. With the FDA approval in 1997 of fomepizole (4-methylpyrazole), the indications for hemodialysis in addition to fomepizole for ethylene glycol poisoning have been examined in recent articles and case reports. Fomepizole, a competitive inhibitor of alcohol dehydrogenase, binds to the same sit...
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ژورنال
عنوان ژورنال: International journal of medicine
سال: 2021
ISSN: ['2309-1622']
DOI: https://doi.org/10.14419/ijm.v9i2.31706