Ethyl Cellulose Microparticles Containing Metformin HCl by Emulsification-Solvent Evaporation Technique: Effect of Formulation Variables
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چکیده
منابع مشابه
Formulation and Evaluation of In-vitro Characterization of Gastic-Mucoadhesive Microparticles/Discs Containing Metformin Hydrochloride
The present study involves preparation and evaluation of gastric-mucoadhesive microparticles with Metformin Hydrochloride as model drug for prolongation of gastric residence time. The microparticles were prepared by the emulsification solvent evaporation technique using polymers of Carbomer 934p (C) and Ethylcellulose (EC). The microparticles were prepared by emulsion solvent evaporation method...
متن کاملFormulation and Evaluation of In-vitro Characterization of Gastic-Mucoadhesive Microparticles/Discs Containing Metformin Hydrochloride
The present study involves preparation and evaluation of gastric-mucoadhesive microparticles with Metformin Hydrochloride as model drug for prolongation of gastric residence time. The microparticles were prepared by the emulsification solvent evaporation technique using polymers of Carbomer 934p (C) and Ethylcellulose (EC). The microparticles were prepared by emulsion solvent evaporation method...
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Objectives: The aim of the present study was to evaluate effects of various polymers on the release of a water soluble drug by using spray drying technique of microencapsulation. Methods: Spray drying is a single step technique, less time is required and loading efficiency is not affected by the nature of the drug whether hydrophilic or hydrophobic. Eudragit RS 30D, RL 30D and Ethylcellulose (S...
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The aim of this study was to investigate the preparation of oil-in-water (O/W) nanoemulsions using an emulsification–evaporation process. Nanoemulsions were formed by homogenizing 10 wt% of an organic phase composed by corn oil and hexane mixed at different ratios, and 90 wt% emulsifier solution containing 1.0 wt % of Tween 20 (T20) or β-lactoglobulin (β-Lg). Nanoemulsions were prepared using a...
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The present study was oriented towards microencapsulation of aspirin and the study of its release kinetics. The desired encapsulation was achieved by emulsion solvent evaporation method using ethyl cellulose (EC), cellulose acetate phthalate (CAP) and their mixture (1:1) of polymeric constituents. Characterization of the formulations was performed by size, shape, drug loading efficiency and in-...
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ژورنال
عنوان ژورنال: ISRN Polymer Science
سال: 2012
ISSN: 2090-8733
DOI: 10.5402/2012/801827