Ethyl 5-(4-Bromophenyl)-4-methyl-1H-pyrrole-2-carboxylate
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چکیده
منابع مشابه
Ethyl 5-(4-Bromophenyl)-4-methyl-1H-pyrrole- 2-carboxylate
This note describes a sequence converting an oxime-substituted pyrrolidine into a trisubstituted pyrrole structure. The synthetic route is based on a double chlorination of the pyrrolidine substrate followed by the base induced formation of both an imine and a nitrile oxide functionality. The latter reacts with an immobilized thiourea to yield an isothiocyanate which upon elimination generates ...
متن کامل2-Ethyl 4-methyl 5-ethyl-3-methyl-1H-pyrrole-2,4-dicarboxylate
The title pyrrole derivative compound, C(12)H(17)NO(4), was synthesized from methyl 3-oxopenta-noate by a Knorr-type reaction and contains a pyrrole ring to which two diagonal alk-oxy-carbonyl groups and two diagonal alkyl substituents are attached. The methyl-carbonyl and ethyl-carbonyl substituents are approximately co-planar with the pyrrole ring, making dihedral angles of 5.64 (2) and 3.44 ...
متن کاملEthyl 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1H-1,2,3-triazole-4-carboxylate
In the title compound, C(10)H(11)ClN(4)O(2)S, the triazole ring carries methyl and ethoxy-carbonyl groups and is bound via a methyl-ene bridge to a chloro-thia-zole unit. There is also evidence for significant electron delocalization in the triazolyl system. Intra- and inter-molecular C-H⋯O hydrogen bonds together with strong π-π stacking inter-actions [centroid-centroid distance 3.620 (1) Å] s...
متن کاملEthyl 5-methyl-1H-pyrrole-2-carboxylate
In the title mol-ecule, C(8)H(11)NO(2), the r.m.s. deviation of non-H atoms from their best plane is 0.031 Å. Mol-ecules are connected via a pair of N-H⋯O hydrogen bonds into a centrosymmetric dimer.
متن کاملEthyl 4-(4-chloroanilino)-1-(4-chlorophenyl)-2-methyl-5-oxo-2,5-dihydro-1H-pyrrole-2-carboxylate
In the title compound, C20H18Cl2N2O3, the dihedral angles between the central 2,5-di-hydro-1H-pyrrole ring and the phenyl rings are 74.87 (9) and 29.09 (9)°. Intra-molecular N-H⋯O and C-H⋯O hydrogen bonds occur. In the crystal, pairs of N-H⋯O hydrogen bonds link adjacent mol-ecules into inversion dimers and form an R 1 (2)(6)R 2 (2)(10)R 1 (2)(6) ring motif through C-H⋯O hydrogen bonds.
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ژورنال
عنوان ژورنال: Molbank
سال: 2017
ISSN: 1422-8599
DOI: 10.3390/m951