Ethanol‐induced inhibition of a neuronal P2X purinoceptor by an allosteric mechanism
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چکیده
منابع مشابه
Mechanism for allosteric inhibition of an ATP-sensitive ribozyme.
We report the structural basis for the modulation of an ATP-sensitive ribozyme that was engineered by modular rational design. This allosteric ribozyme is composed of two independently functioning domains, one a receptor for ATP and the other a self-cleaving ribozyme. When fused in the appropriate fashion, the conjoined aptamer-ribozyme construct functions as an allosteric ribozyme that is inhi...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1998
ISSN: 0007-1188,1476-5381
DOI: 10.1038/sj.bjp.0701599