Estrogen in Luteal Phase Support: Effects on IVF-ICSI Antagonist Protocol Pregnancy Results

Aim: This study aimed to investigate the effect of luteal phase support (LPS) with estradiol in addition progesterone on pregnancy outcomes patients who underwent ovulation induction GnRH antagonist protocol vitro fertilization- intracytoplasmic sperm injection (IVF-ICSI).
 Materials and Methods: retrospective was carried out at reproductive medicine center Necmettin Erbakan University Meram Medical Faculty. The enrolled 128 undergoing ICSI an for controlled ovarian hyperstimulation. Study group administered 7.8 mg transdermal (E2) daily LPS (n=64). Control only All women received 200 3x1 intravaginal 50 intramuscular per two days LPS. Blood samples were drawn 12 after embryo transfer β-hCG. If result is negative, treatment discontinued, if positive, discontinued continued until 10th week gestation. Pregnancy main endpoint.
 Results: There no difference between groups terms biochemical pregnancy, clinical abortus ongoing rates.
 Conclusion: In our study, use estrogen did not show any outcomes.