Estimation of hemoglobin, serum iron, total iron-binding capacity and serum ferritin levels in oral submucous fibrosis: A clinicopathological study

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Estimation of hemoglobin, serum iron, total iron-binding capacity and serum ferritin levels in oral submucous fibrosis: A clinicopathological study

INTRODUCTION Oral submucous fibrosis (OSMF) is also considered as an Asian version of sideropenic dysphagia, wherein chronic iron deficiency leads to mucosal susceptibility to irritants, such as chillies and areca nut products. Hemoglobin (Hb) levels, in particular, serum iron levels, are considered as biochemical indicators for nutritional assessment. Serum iron content can thus be a predictor...

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Serum iron and total iron-binding capacity compared with serum ferritin in assessment of iron deficiency.

Ferritin values for 250 selected sera were compared with values for iron, total iron-binding capacity (TIBC), and transferrin saturation, to assess the potential of the ferritin assay for the detection of latent iron deficiency. The specimens were grouped (50 in each group) according to their values for iron and TIBC. In Group 1 (low iron, high TIBC) the saturation and ferritin values both indi...

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Role of Hemoglobin and Serum Iron in Oral Submucous Fibrosis: A Clinical Study

BACKGROUND Oral submucous fibrosis is a chronic, insidious oral mucosal condition affecting the most parts of the oral cavity with high malignant transformation rate triggered by areca nut chewing, nutritional deficiencies, immunologic processes, and genetic predisposition. OSF causes significant hematological abnormalities resulting in anemia and a decrease in serum iron levels. AIM The aim ...

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Simplified determination of serum iron and total iron-binding capacity.

2,4,6-Tripyridyl-s-triazine (TPTZ) is a color reagent for ferrous ion in the pH range 2 to 10,when ascorbic acid is used as the reducing agent. In this range TPTZ and ferrous ion combine in the ratio of two to one. Tris buffer is commonly used to maintain an alkaline pH, but it reacts with other reducing agents, rendering them ineffective. These observations suggested a method for the joint det...

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Quantitative evaluation of serum iron, ferritin and Total iron binding capacity (T.I.B.C.) in patients with oral cancer and pre cancers

Iron is an essential nutrient playing a central role in metabolism and also is an essential component in DNA synthesis and respiratory and oxidative metabolism which relate to the properties of unremitting proliferation and a more anaerobic metabolism that may contribute to a selective advantage of neoplastic cells over non neoplastic cells. Clinical correlations have been made linking cellular...

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ژورنال

عنوان ژورنال: Journal of Oral and Maxillofacial Pathology

سال: 2017

ISSN: 0973-029X

DOI: 10.4103/jomfp.jomfp_131_15