Estimation of amlodipine besylate, valsartan and hydrochlorothiazide in bulk mixture and tablet by UV spectrophotometry

Estimation of Amlodipine Besylate, Valsartan and Hydrochlorothiazide in Bulk Mixture and Tablet by UV Spectrophotometry

A simple, precise, accurate and economic simultaneous UV spectrophotometric method has been developed for the estimation of amlodipine besylate, valsartan and hydrochlorothiazide in combination in bulk mixture and tablet. The estimation was based upon measurement of absorbance at absorbance maxima of 359 nm, 317 nm and 250 nm for amlodipine besylate, hydrochlorothiazide and valsartan in methano...

Spectrophotometric Estimation of Amlodipine Besylate in Bulk and in Tablet Dosage Form

A simple UV spectrophotometric method for the analysis of Amlodipine Besylate was developed to analyze the drug in bulk and in tablet formulation. In this method the simple UV spectrum of Amlodipine Besylate in aqueous ethanol (30% v/v) was obtained which exhibits absorption maxima (λ max) at 239.40 nm. The Beers law ranges was followed in the concentration range of 5-60 μg/ml. The proposed met...

Stability-indicating method for simultaneous estimation of olmesartan medoxomile, amlodipine besylate and hydrochlorothiazide by RP-HPLC in tablet dosage form.

A simple, specific, accurate and precise stability-indicating reversed-phase high-performance liquid chromatographic method was developed for simultaneous estimation of olmesartan medoxomile (OLME), amlodipine besylate (AMLO) and hydrochlorothiazide (HCTZ) in tablet dosage form. The method was developed using an RP C18 base deactivated silica column (250 × 4.6 mm, 5 µm) with a mobile phase cons...

UV-Visible spectrophotometry of Repaglinide in bulk and in formulation by using methyl orange as reagents

Two sensitive spectrophotometric methods are presented for the assay of Repaglinide in bulkdrug and in formulations using methyl orange, as reagents. Oxidant by reacting with a fixedamount of either methyl orange and measuring the absorbance at 485.2 nm (method-I) andmeasuring the absorbance at 618.9 nm (method-II). Developed method is based on the formationof extractable colored complex of dru...

Exforge HCT, INN-amlodipine + valsartan + hydrochlorothiazide