Establishing Normal Reference Ranges in Pediatric Patients

Establishing Reference Ranges of Hematological Parameters from Malian Healthy Adults

Introduction Measurement of immuno-hematological parameters has been historically helpful in the diagnosis and treatment monitoring of many infectious diseases and cancers. However, these parameters have not yet been established in many developing countries where patient care strongly relies on such low-cost tests. This study describes the immuno-hematological parameter ranges for Malian health...

Establishing pediatric reference intervals: a challenging task.

Defining pediatric reference intervals (RIs) is one of the most difficult tasks in our profession. The continuously changing physiology of growing children makes their laboratory values a moving target. To measure specific analytes in the pediatric age range, one has to consider the interindividual variation of not only the homeostatic set point but also the developmental stage of each individu...

A Description of Reference Ranges for Organic Acids in Urine Samples from A Pediatric Population in Iran

Background: Organic acids refer to a family of compounds that are intermediates in a variety of metabolic pathways. Many organic acids are present in urine from clinically normal individuals. Elevated levels of urine organic acids cause to the organic acidurias, disorders in which some metabolic pathways in organic acid metabolism are blocked. The present work identified major and minor urinary...

Normal reference ranges for echocardiography: do we really need more?

Echocardiography is themostwidelyusednon-invasivecardiac imaging for assessing the cardiac structure and function. Echocardiography has the advantage of low cost, no radiation risk, and great availability. However, as for any diagnostic test, its interpretation depends on its ability to accurately detect abnormalities. Actually, the definition of ‘abnormal’ relies on the definition of ‘normal’ ...

Are TSH normal reference ranges adequate for pregnant women?