Establishing a genomic database for the medicinal plants in the Brazilian Pharmacopoeia

Abstract Background Brazil is exceptionally abundant in medicinal plant resources and has a rich ethnopharmacological history. Brazilian Pharmacopoeia (BP) acts as national standard that regulates drug quality six published editions. Recent genomic approaches have led to resurgence of interest herbal drugs. The data plants been used for pharmaceutical applications, protecting natural resources, efficiently regulating the market. However, there are few databases specifically plants, establishment database focuses on herbs contained BP urgently required. Methods species included each edition were analyzed understand evolution 82 collected categorized into four sections: DNA barcodes, super-barcodes, genomes, sequencing data. A typical web server architecture pattern was build website. Furthermore, cp-Gs Aloe genus an illustration. Results new database, Genomic Database (BPGD) constructed now publicly accessible. BLAST identification sequence searching with internal transcribed spacer 2 (ITS2), intergenic region ( psb A- trn H), chloroplast genome (cp-G) also embedded BPGD. 753 ITS2 76 species, 553 -trn H 190 genomes (whole genome) 57 species. In addition, it contains 37 sets 24 616 transcriptome 34 includes 187 representing BP. Analyses three identified variable regions cp-Gs. These can be identify intraspecific relationships. Conclusions This study presents first listed latest It serves efficient platform obtain analyze data, accelerate studies regarding facilitate rational development their market regulation.