Establishing a clinical trial battery for Huntington disease
نویسندگان
چکیده
منابع مشابه
Method for establishing authorship in a multicenter clinical trial.
With the emergence of large multicenter trials over the past 20 years, the numbers of investigators involved and publications resulting from each study have grown exponentially. An efficient, fair, and effective way to establish authorship on study-related manuscripts could diminish conflict among the investigators and help ensure robust and timely dissemination of study results. This article d...
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OBJECTIVE To describe the clinical presentation a group of patients with juvenile onset of Huntington disease. METHOD All patients were interviewed following a structured clinical questionnaire. Patients were genotyped for the trinucleotide cytosine-adenine-guanine (CAG) repeat in the Huntington Disease gene. High resolution brain MRI was performed in all patients. RESULTS We identified 4 p...
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ژورنال
عنوان ژورنال: Nature Reviews Neurology
سال: 2012
ISSN: 1759-4758,1759-4766
DOI: 10.1038/nrneurol.2012.67