Essential Oils of Two Vietnamese Plants <i>Piper betle</i> f. <i>densum</i> (Piperaceae) and <i>Disepalum plagioneurum</i> (Annonaceae): Chemical Composition, Antimicrobial, and Cytotoxic Activities

The chemical compositions were determined by the leaf essential oils of 2 Vietnamese plants, Piper betle f. densum and Disepalum plagioneurum. main classes in P oil sesquiterpene hydrocarbons (30.1%) oxygenated sesquiterpenes (60.1%), with γ-elemene (12.7%), valeranone (9.3%), ishwarone (6.0%) being principal compounds. plagioneurum was dominated monoterpene (23.9%) (59.8%). Bicyclogermacrene (26.8%), ( E)-caryophyllene E)- β-ocimene (8.4%), Z)- major compounds this oil. With same MIC 64 µg/mL, D strongly controlled growth Gram (+) bacterium Clostridium sporogenes NCTC 12935 fungus Aspergillus niger ATCC 1015, respectively. It also found that cytotoxic to cancer cell lines MCF7 HeLa IC 50 values 63.2 41.4