espC Pathogenicity Island of Enteropathogenic Escherichia coli Encodes an Enterotoxin
نویسندگان
چکیده
منابع مشابه
espC pathogenicity island of enteropathogenic Escherichia coli encodes an enterotoxin.
At least five proteins are secreted extracellularly by enteropathogenic Escherichia coli (EPEC), a leading cause of infant diarrhea in developing countries. However only one, EspC, is known to be secreted independently of the type III secretion apparatus encoded by genes located within the 35.6-kb locus of enterocyte effacement pathogenicity island. EspC is a member of the autotransporter famil...
متن کاملgenetic evaluation of locus of enterocyte effacement pathogenicity island (lee) in enteropathogenic escherichia coli isolates (epec).
background and objectives: enteropathogenic escherichia coli (epec) divided into two groups typical and atypical (aspect). the main virulence genes are located in a pathogenicity island called lee ( locus of enterocyte effacement ). lee frequently inserted in trna genes of selc , pheu and phev in the bacterial chromosome. tepec and aepec strains have some differences in their pathogenicity. the...
متن کاملGenetic evaluation of Locus of enterocyte effacement pathogenicity island (LEE) in Enteropathogenic Escherichia coli isolates (EPEC)
BACKGROUND AND OBJECTIVES Enteropathogenic Escherichia coli (EPEC) divided into two groups typical and atypical (aspect). The main virulence genes are located in a pathogenicity island called LEE (Locus of Enterocyte Effacement). LEE frequently inserted in tRNA genes of selC, pheU and pheV in the bacterial chromosome. tEPEC and aEPEC strains have some differences in their pathogenicity. The pur...
متن کاملPrevalence and characteristics of the O122 pathogenicity island in typical and atypical enteropathogenic Escherichia coli strains.
The presence of the pathogenicity island (PAI) O122 genes, efa1 (lifA), sen, pagC, nleB, and nleE, in typical and atypical enteropathogenic Escherichia coli (EPEC) strains was investigated. The simultaneous occurrence of all genes was statistically associated with diarrhea due to atypical EPEC. Detection of the complete PAI O122 could aid in the identification of potential pathogenic strains of...
متن کاملA cloned pathogenicity island from enteropathogenic Escherichia coli confers the attaching and effacing phenotype on E. coli K-12.
Attaching and effacing (AE) bacteria are a diverse group of gastrointestinal pathogens, comprising members of four genera, that cause the intestinal epithelial microvilli to be replaced with raised clusters of filamentous actin that conform to the surface of attached bacteria. We have cloned a 35.4 kb 'pathogenicity island' from the prototype AE bacterium, enteropathogenic Escherichia coli, con...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2001
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.69.1.315-324.2001