Escherichia coli mutants deficient in guanine-xanthine phosphoribosyltransferase
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چکیده
منابع مشابه
Thymineless death in recombination deficient mutants of Escherichia coli K12.
When grown in thymine-free minimal synthetic medium, thyA recA mutants of Escherichia coli K12 were comparatively more resistant and thyA recBC mutants more sensitive to thymineless death (TLD) than their respective parent strains. No excessive numbers of single-strand breaks were observed in the DNA of the recBC mutant strain starved for thymine, hence the hypersensitivity for TLD in this stra...
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Naturally occurring mutations in hypoxanthine-guanine phosphoribosyltransferase (HPRT) have been identified by amino acid sequencing, cDNA cloning, and direct nucleotide sequencing of PCR-amplified transcripts. To determine the effect these mutations have on the catalytic properties of the molecule, knowledge of the three-dimensional structure of HPRT is required. A prerequisite for this, howev...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1976
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.126.3.1141-1148.1976