Escaping enzalutamide: Malat1 contributes to resistance
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A MALAT1/HIF-2α feedback loop contributes to arsenite carcinogenesis
Arsenic is well established as a human carcinogen, but the molecular mechanisms leading to arsenic-induced carcinogenesis are complex and elusive. It is also not known if lncRNAs are involved in arsenic-induced liver carcinogenesis. We have found that MALAT1, a non-coding RNA, is over-expressed in the sera of people exposed to arsenite and in hepatocellular carcinomas (HCCs), and MALAT1 has a c...
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ژورنال
عنوان ژورنال: Nature Reviews Urology
سال: 2017
ISSN: 1759-4812,1759-4820
DOI: 10.1038/nrurol.2017.91