Erythrosine is a potential photosensitizer for the photodynamic therapy of oral plaque biofilms

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Erythrosine is a potential photosensitizer for the photodynamic therapy of oral plaque biofilms.

OBJECTIVES The purpose of this study was to evaluate the clinical plaque disclosing agent erythrosine as a photosensitizer in the photodynamic killing of the oral bacterium Streptococcus mutans grown as a biofilm. METHODS S. mutans biofilms of 200 microm thickness were grown in a constant-depth film fermenter. In addition to determining localization of the photosensitizer within biofilms usin...

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Enhancement of erythrosine-mediated photodynamic therapy of Streptococcus mutans biofilms by light fractionation.

OBJECTIVES We aimed to increase the bacterial cell killing efficacy of erythrosine-mediated photodynamic therapy (PDT) of Streptococcus mutans biofilms by fractionating the delivered light dose into a series of shorter pulses. METHODS S. mutans biofilms of 200 microm thickness were grown in a constant-depth film fermenter (CDFF). Biofilms were incubated with 22 microM erythrosine before being...

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Polymeric photosensitizer prodrugs for photodynamic therapy.

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ژورنال

عنوان ژورنال: Journal of Antimicrobial Chemotherapy

سال: 2006

ISSN: 1460-2091,0305-7453

DOI: 10.1093/jac/dkl021