Erythropoietin accelerates functional recovery after moderate sciatic nerve crush injury
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چکیده
منابع مشابه
Crocin Enhanced Functional Recovery after Sciatic Nerve Crush Injury in Rats
Objective(s): Crocin is a constituent of saffron and has many biological functions. The present study aimed to investigate the effects of intraperitoneal (IP) injection of crocin on sciatic nerve regeneration in male Wistar rats. Materials and Methods: Fifty-four rats were divided into 9 groups: groups 1-4 (intact + normal saline and intact + crocin at doses of 5, 20 and 80 mg/kg, respectively)...
متن کاملCelecoxib accelerates functional recovery after sciatic nerve crush in the rat
The inflammatory response appears to be essential in the modulation of the degeneration and regeneration process after peripheral nerve injury. In injured nerves, cyclooxygenase-2 (COX-2) is strongly upregulated around the injury site, possibly playing a role in the regulation of the inflammatory response. In this study we investigated the effect of celecoxib, a COX-2 inhibitor, on functional r...
متن کاملcrocin enhanced functional recovery after sciatic nerve crush injury in rats
objective(s): crocin is a constituent of saffron and has many biological functions. the present study aimed to investigate the effects of intraperitoneal (ip) injection of crocin on sciatic nerve regeneration in male wistar rats. materials and methods: fifty-four rats were divided into 9 groups: groups 1-4 (intact + normal saline and intact + crocin at doses of 5, 20 and 80 mg/kg, respectively)...
متن کاملFunctional recovery after facial and sciatic nerve crush injury in the rat.
OBJECTIVES To systematically record rat facial nerve recovery following crush injury to the main trunk with respect to ocular and vibrissial function and to compare the rates of facial and sciatic nerve recovery from crush injury in the same animals. This serves as a means of validating the functional parameters of facial nerve recovery against the well-known measure of hind limb function, the ...
متن کاملDexamethasone Enhanced Functional Recovery after Sciatic Nerve Crush Injury in Rats
Dexamethasone is currently used for the treatment of peripheral nerve injury, but its mechanisms of action are not completely understood. Inflammation/immune response at the site of nerve lesion is known to be an essential trigger of the pathological changes that have a critical impact on nerve repair and regeneration. In this study, we observed the effects of various doses of dexamethasone on ...
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ژورنال
عنوان ژورنال: Muscle & Nerve
سال: 2017
ISSN: 0148-639X
DOI: 10.1002/mus.25459