منابع مشابه
Erythropoietic function in dilution anemia.
By ALLAN J. EIISLEV D ILUTION ANEMIA 011 HYDIIE\IIA is a condition characterized by an increase in total plasma volume without corresponding change in total red cell volume. Certain anemias complicating pregnancy,’ malnutrition,2 netirasthenia,3 and the t.herapetttic use of phenylbutazone4 and steroids5 have been considered to he caused by such a dilution of the red cell mass. The erythropoieti...
متن کاملRecent advances in erythropoietic agents in renal anemia.
Red cell production in chronic kidney disease is usually too low to maintain a normal haemoglobin, and thus anaemia develops in a large proportion of patients. The ability to stimulate erythropoiesis in the bone marrow by the use of therapeutic agents has only been possible in the last 20 years, initially with recombinant human erythropoietin (epoetin), and later darbepoetin alfa. Many new agen...
متن کاملVariability of the Erythropoietic Response in Autoimmune Hemolytic Anemia :
One hundred-nine cases of autoimmune hemolysis were reviewed to determine the frequency of reticulocytopenia. the state of the erythroid marrow in reticulocytopenic cases. and the course of reticulocyte production indices with time and glucocorticoid treatment. The mean hematocrit at presentation was 24 mL/dL, but 30% of cases had an initial hematocrit <20 mi/dI. Median reticulocyte percentage ...
متن کاملAdriamycin-induced delayed erythropoietic injury expressed following anemia stress.
The present studies were undertaken to compare anemia-induced erythropoietic responses in femoral marrows and spleens of mice pretreated with Adriamycin (ADR) or 1-beta-D-arabinofuranosylcytosine with those of untreated age-matched controls. Mice were bled 45 or 120 days after drug treatment. The erythropoietic response to bleeding was quantitated by morphological, gravimetric, and radioiron me...
متن کاملSuppression of hepcidin during anemia requires erythropoietic activity.
Hepcidin, the principal iron regulatory hormone, regulates the absorption of iron from the diet and the mobilization of iron from stores. Previous studies indicated that hepcidin is suppressed during anemia, a response that would appropriately increase the absorption of iron and its release from stores. Indeed, in the mouse model, hepcidin-1 was suppressed after phlebotomy or erythropoietin adm...
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ژورنال
عنوان ژورنال: Blood
سال: 1955
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v10.6.616.616