Erythropoiesis stimulating agents and reno-protection: a meta-analysis
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چکیده
منابع مشابه
Erythropoiesis stimulating agents and reno-protection: a meta-analysis
BACKGROUND Erythropoiesis stimulating agents (ESAs) were proposed to enhance survival of renal tissues through direct effects via activation of EPO receptors on renal cells resulting in reduced cell apoptosis, or indirect effects via increased oxygen delivery due to increased numbers of Hb containing red blood cells. Thus through several mechanisms there may be benefit of ESA administration on ...
متن کاملIntravenous iron and erythropoiesis‐stimulating agents in haemodialysis: A systematic review and meta‐analysis
AIM Higher dosages of erythropoiesis-stimulating agents (ESAs) have been associated with adverse effects. Intravenous iron is used to optimize ESA response and reduces ESA doses in haemodialysis patients; this meta-analysis evaluates the magnitude of this effect. METHODS A literature search was performed using MEDLINE, Embase and the Cochrane Collaboration Central Register of Clinical Trials ...
متن کاملBenefits and harms of erythropoiesis-stimulating agents for anemia related to cancer: a meta-analysis.
BACKGROUND Erythropoiesis-stimulating agents are used to treat anemia in patients with cancer. However, their safety and effectiveness is controversial. We did a systematic review of the clinical efficacy and harms of these agents in adults with anemia related to cancer or chemotherapy. METHODS We conducted a systematic review of published and unpublished randomized controlled trials (RCTs) u...
متن کاملSafety and efficacy outcomes with erythropoiesis-stimulating agents in patients with breast cancer: a meta-analysis.
BACKGROUND New data on erythropoiesis-stimulating agents (ESAs) regarding overall survival and disease progression-related outcomes in patients with breast cancer receiving chemotherapy are presented in a meta-analysis of controlled trials of ESA use (epoetin α, epoetin β, darbepoetin α, biosimilars). PATIENTS AND METHODS A literature search identified reports from January 1997 through March ...
متن کاملEffects of erythropoiesis-stimulating agents on heart failure patients with anemia: a meta-analysis
INTRODUCTION Heart failure (HF) is always complicated with anemia and is associated with bad prognosis in this patient population. Several studies have assessed the potential role of erythropoietin-stimulating agent (ESA) in improving cardiac function and reducing the number of hospitalizations in anemic patients with HF. AIM We performed a meta-analysis to assess the potential role of ESA in...
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ژورنال
عنوان ژورنال: BMC Nephrology
سال: 2017
ISSN: 1471-2369
DOI: 10.1186/s12882-017-0438-4