ERR1- and PGC1α-associated mitochondrial alterations correlate with pan-cancer disparity in African Americans

Increasing Disparity in Colorectal Cancer Incidence and Mortality Among African Americans and Whites: A State's Experience.

KEY WORDS Objectives: To measure disparities between African Americans and whites in colorectal cancer incidence and mortality rates between 1995-2006 in Wisconsin. Methods: Cancer incidence data were obtained from the Wisconsin Cancer Reporting System. Cancer mortality data were accessed from the SEER. Trends in incidence and mortality rates were calculated and changes in relative disparity we...

African Ancestry Is Associated with Asthma Risk in African Americans

BACKGROUND Asthma is a common complex condition with clear racial and ethnic differences in both prevalence and severity. Asthma consultation rates, mortality, and severe symptoms are greatly increased in African descent populations of developed countries. African ancestry has been associated with asthma, total serum IgE and lower pulmonary function in African-admixed populations. To replicate ...

Lung cancer in African Americans.

Susceptibility to lung cancer in light smokers associated with CYP1A1 polymorphisms in Mexican- and African-Americans.

The gene-environment associations between potential carcinogenic agents modified by polymorphisms in the cytochrome P450 1A1 (CYP1A1) gene and lung cancer risk were assessed in a hospital-based case-control study composed of African- and Mexican-Americans. The study involved 171 cases and 295 controls identified from the greater Houston and San Antonio metropolitan areas. Both the exon 7 and Ms...

Rates and factors associated with falls in older European Americans, Afro-Caribbeans, African-Americans, and Hispanics

PURPOSE To evaluate rates and factors associated with older adult falls in different ethnic groups. PARTICIPANTS AND METHODS Information on demographics, medical and falls history, and pain and physical activity levels was collected from 550 community-dwelling older adults (75±9 years old, 222 European Americans, 109 Afro-Caribbeans, 106 African-Americans, and 113 Hispanics). RESULTS Taking...