Epitope Mapping of Dengue-Virus-Enhancing Monoclonal-Antibody Using Phage Display Peptide Library
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چکیده
منابع مشابه
Epitope Mapping of Dengue-Virus-Enhancing Monoclonal-Antibody Using Phage Display Peptide Library
The Antibody-Dependent Enhancement (ADE) hypothesis has been proposed to explain why more severe manifestations of Dengue Hemorrhagic Fever and Dengue Shock Syndrome (DHF/DSS) occur predominantly during secondary infections of Dengue Virus (DV) with different serotypes. However, the epitopes recognized by these enhancing antibodies are unclear. Recently, antipre-M monoclonal antibody (mAb 70-21...
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ژورنال
عنوان ژورنال: American Journal of Infectious Diseases
سال: 2008
ISSN: 1553-6203
DOI: 10.3844/ajidsp.2008.76.84