منابع مشابه
Landau-Kleffner Syndrome: An Acquired Epileptic Aphasia.
Landau-Kleffner syndrome is characterized by a complex group of symptoms including deterioration in language skills, seizures, and abnormal electroencephalography findings. A six-year-old male patient had aphasia for three years and generalized tonic-clonic epileptic seizures for two years. Pure-tone audiometry and auditory brain-stem response audiometry findings were normal. He had verbal audi...
متن کاملLandau-Kleffner syndrome: acquired epileptic aphasia in children.
Acquired epileptic aphasia, or Landau-Kleffner syndrome (LKS), once thought to be a rare syndrome, may occur more frequently in the pediatric population than once thought. This syndrome is typically characterized by an abrupt or gradual loss of language ability and inattentiveness to sound, sometimes called auditory agnosia, with onset during the first 5 years of life. This interruption in comm...
متن کاملAcquired Aphasia in Children
Acquired childhood aphasia is rare but has important conceptual implications for developmental neuropsychology. The last 15 years have seen major changes in their clinical description, which have led to the awareness that the syndromes in acquired childhood aphasia are more similar to the syndromes in adult aphasia than previously thought. This article briefly discusses the definition and diffe...
متن کاملMagnetoencephalography in children with Landau-Kleffner syndrome and acquired epileptic aphasia.
BACKGROUND AND PURPOSE Landau-Kleffner syndrome (LKS) is epileptiform aphasia acquired during childhood and occurring in children with previously normal language development. The epileptiform activity in these children is thought to result in a functional ablation of eloquent speech areas. The purpose of this study was to investigate the usefulness of magnetoencephalography (MEG) for localizing...
متن کاملA de novo loss-of-function GRIN2A mutation associated with childhood focal epilepsy and acquired epileptic aphasia
OBJECTIVE N-methyl-D-aspartate receptors (NMDAR) subunit GRIN2A/GluN2A mutations have been identified in patients with various neurological diseases, such as epilepsy and intellectual disability / developmental delay (ID/DD). In this study, we investigated the phenotype and underlying molecular mechanism of a GRIN2A missense mutation identified by next generation sequencing on idiopathic focal ...
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ژورنال
عنوان ژورنال: Pediatric Neurology Briefs
سال: 1991
ISSN: 2166-6482,1043-3155
DOI: 10.15844/pedneurbriefs-5-9-9