Epigenetic regulation during mammalian oogenesis
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Title: Epigenetic regulation during mammalian oogenesis
The advent of the epigenetic era has sparked a new frontier in molecular research and the understanding of how development can be regulated beyond direct alterations of the genome. Thus far, the focal point of epigenetic regulation during development has been chromatin modifications that control differential gene expression by DNA methylation and histone alterations. But what of events that alt...
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Epigenetics is the study of phenotypic variation arising from developmental and environmental factors regulating gene transcription at molecular, cellular, and physiological levels. A naturally occurring biological process driven by epigenetics is the egg-to-embryo developmental transition when two fully differentiated adult cells - egg and sperm - revert to an early stem cell type with totipot...
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ژورنال
عنوان ژورنال: Reproduction, Fertility and Development
سال: 2008
ISSN: 1031-3613
DOI: 10.1071/rd07181