Epigenetic engineering shows that a human centromere resists silencing mediated by H3K27me3/K9me3
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منابع مشابه
Epigenetic engineering shows that a human centromere resists silencing mediated by H3K27me3/K9me3
Centromeres are characterized by the centromere-specific H3 variant CENP-A, which is embedded in chromatin with a pattern characteristic of active transcription that is required for centromere identity. It is unclear how centromeres remain transcriptionally active despite being flanked by repressive pericentric heterochromatin. To further understand centrochromatin's response to repressive sign...
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ژورنال
عنوان ژورنال: Molecular Biology of the Cell
سال: 2016
ISSN: 1059-1524,1939-4586
DOI: 10.1091/mbc.e15-08-0605