Epigenetic engineering and the art of epigenetic manipulation
نویسندگان
چکیده
منابع مشابه
Cardiomyocyte Marker Expression in Mouse Embryonic Fibroblasts by Cell-Free Cardiomyocyte Extract and Epigenetic Manipulation
Background: The regenerative capacity of the mammalian heart is quite limited. Recent reports have focused on reprogramming mesenchymal stem cells into cardiomyocytes. We investigated whether fibroblasts could transdifferentiate into myocardium.Methods: Mouse embryonic fibroblasts were treated with Trichostatin A (TSA) and 5-Aza-2-Deoxycytidine (5-aza-dC). The treated cells were permeabilized w...
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ژورنال
عنوان ژورنال: Genome Biology
سال: 2014
ISSN: 1465-6906
DOI: 10.1186/gb4179