Epigallocatechin-3-gallate inhibits bacterial virulence and invasion of host cells
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منابع مشابه
(-)-Epigallocatechin-3-gallate induces apoptosis and inhibits invasion and migration of human cervical cancer cells.
Invasion and metastasis are the major causes of cancer-related death. Pharmacological or therapeutic interventions such as chemoprevention of the progression stages of neoplastic development could result in substantial reduction in the incidence of cancer mortality. (-)-Epigallocatechin-3-gallate (EGCG), a promising chemopreventive agent, has attracted extensive interest for cancer therapy util...
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Inflammatory Breast Cancer (IBC) is a highly aggressive form of cancer characterized by high rates of proliferation, lymphangiogenesis and metastasis, and an overall poor survival. As regular green tea consumption has been associated with improved prognosis of breast cancer patients, including decreased risk of recurrence, here the effects of the green tea polyphenol epigallocatechin-3-gallate ...
متن کاملDifferentiation-Inducing Activity of the Phyto-polyphenols Epigallocatechin-3-gallate and Kaempferol on NB4 Cells
Background and Objective: The rate of survival in acute promyelocytic leukemia (APL) can dramatically improve, if the patients receive all-trans-retinoic acid (ATRA) treatment. However, this drugchr('39')s toxicity is a major problem in APL treatment. Previous researches have demonstrated that phyto-polyphenols such as epigallocatechin gallate (EGCG) and kaempferol cause apoptosis in hematopoie...
متن کاملEffect of epigallocatechin-3-gallate on graft-versus-host disease.
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is often complicated by alloreactive donor T-cell-mediated graft-versus-host disease (GvHD). The major polyphenol of green tea, epigallocatechin-3-gallate (EGCG), is an inhibitor of both DNA methyltransferase 1 (DNMT1) and signal transducer and activator of transcription 1 (STAT1), which are essential for induction of GvHD. Thus, in...
متن کاملGreen tea extract, epigallocatechin-3-gallate, inhibits the growth and invasive ability of human glioma cells.
Epigallocatechin-3-gallate (EGCG) is a major constituent of green tea, but its effects on glioma cell growth have not been reported. The aim of this study was to investigate the anticancer effect of EGCG on the growth and invasive ability of glioma cells, as well as the molecular mechanisms responsible for it. Two glioma cell lines were treated with EGCG, and its effect on cell proliferation an...
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ژورنال
عنوان ژورنال: Bioorganic & Medicinal Chemistry
سال: 2017
ISSN: 0968-0896
DOI: 10.1016/j.bmc.2017.03.023