منابع مشابه
Intrathecal and epidural narcotics.
This paper presents an overall review of epidural and intrathecal narcotics. The early laboratory studies and initial clinical applications are presented. This is followed by a description of the mechanism of action of narcotics acting both intrathecally and epidurally, and some of the similarities and differences between narcotics and local anesthetic drugs. Technique, dosages, indications, an...
متن کاملEpidural, intrathecal pharmacokinetics, and intrathecal bioavailability of ropivacaine.
BACKGROUND Ropivacaine is used by the epidural route for postoperative pain management with various neuraxial techniques. Given the widespread use of these techniques and the relative paucity of data on spinal disposition of local anesthetics, we evaluated through an experimental animal model, the spinal disposition of ropivacaine, allowing further studies of factors influencing their intrathec...
متن کاملIntrathecal morphine reduces breakthrough pain during labour epidural analgesia.
BACKGROUND When using the combined spinal-epidural (CSE) technique for labour analgesia, parturients often experience breakthrough pain after the spinal medication has receded. We tested the hypothesis that a small dose of intrathecal morphine would reduce breakthrough pain. METHODS This was a randomized, double-blind, placebo-controlled trial. Subjects were randomized to receive either 100 m...
متن کاملOBSTETRICS Intrathecal morphine reduces breakthrough pain during labour epidural analgesia
Methods. This was a randomized, double-blind, placebo-controlled trial. Subjects were randomized to receive either 100 mg of morphine (MS) or placebo (PLCB) with the spinal injection of bupivacaine and fentanyl. Assessments included need for supplementation during labour analgesia, use of pain medications for 24 h after delivery, and side-effects. The primary endpoint was the rate of breakthrou...
متن کاملEpidural versus intrathecal morphine for postoperative analgesia after Caesarean section.
BACKGROUND Perispinal anaesthesia for Caesarean section allows injection of epidural (ED) or intrathecal (i.t.) morphine to provide long-lasting postoperative analgesia. To compare these two routes, a prospective, randomized, double-blinded study of 53 patients undergoing elective Caesarean section was performed. METHODS Combined spinal-epidural anaesthesia with 6 mg of i.t. hyperbaric bupiva...
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ژورنال
عنوان ژورنال: Canadian Anaesthetists’ Society Journal
سال: 1983
ISSN: 0008-2856,1496-8975
DOI: 10.1007/bf03015240