Epidermal growth factor receptor inhibitors related trichomegaly of Eyelashes
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منابع مشابه
Epidermal growth factor receptor inhibitors related trichomegaly of Eyelashes
Advances in understanding of the mechanisms involved in oncogenesis have led to the development of targeted therapies such as epidermal growth factor receptor inhibitors (EGFRIs), targeting a variety of molecular structures and able to inhibit aberrantly activated oncogenic pathways. Their use made treatment more tolerable with significant reduction of systemic adverse effects. However, EGFRIs ...
متن کاملTrichomegaly of the eyelashes after lung cancer treatment with the epidermal growth factor receptor inhibitor erlotinib.
REFERENCES 1. Lam JS, Shvarts O, Leppert JT, et al: Postoperative surveillance protocol for patients with localized and locally advanced renal cell carcinoma based on a validated prognostic nomogram and risk group stratification system. J Urol 174:466-472, 2005 2. Brugarolas J: Renal-cell carcinoma: Molecular pathways and therapies. N Engl J Med 356:185-187, 2007 3. Motzer RJ, Hutson TE, Tomcza...
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Epithelial growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) have been widely used for non-small-cell lung cancer patients. Its untoward cutaneous effects are largely well known and developed in many patients treated with EGFR TKIs. However trichomegaly of eyelash is rarely reported. Although trichomegaly is not a drug-limiting side effect, it could be troublesome of continuing th...
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EGFR is a key molecule in cancer cells. EGFR signaling was shown to promote tumor cell proliferation and survival, invasion and angiogenesis and mediate resistance to treatment, including ionizing radiation in preclinical models. We extracted proteins from astrocytoma (III and IV) oligodendroglioma(IV) tumors and normal brain tissues and then evaluated the protein purity by Bradford test ...
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ژورنال
عنوان ژورنال: Oxford Medical Case Reports
سال: 2014
ISSN: 2053-8855
DOI: 10.1093/omcr/omu038