Epidemiology, Biology, Treatment, and Prevention of Ductal Carcinoma In Situ (DCIS)
نویسندگان
چکیده
منابع مشابه
Ductal carcinoma in situ (DCIS) in Karachi.
OBJECTIVE To study the frequency of ductal carcinoma in situ (DCIS) in a large pathology series. DCIS is a proliferation of non-invasive, malignant epithelial cells within the ductolobular system of the breast. It is a heterogeneous entity with several morphologic variants that differ in gross appearance, growth pattern, cytologic features, mammography, and malignant potential. METHODS The da...
متن کاملDiagnosis and management of ductal carcinoma in situ (DCIS).
OBJECTIVES Systematic synthesis of the published evidence about incidence, risk factors, and management options for women with ductal carcinoma in situ (DCIS) of the breast. DATA SOURCES Original epidemiologic studies were sought from several databases to identity articles published in English between 1970 and January 31, 2009. REVIEW METHODS Incidence of DCIS in the general population and ...
متن کاملDuctal carcinoma in situ (DCIS) of the breast: perspectives on biology and controversies in current management.
The incidence of ductal carcinoma in situ (DCIS) has increased because of increasing use of sensitive imaging modalities. MRI is commonly used for the detection of breast cancer but has not yet been validated in randomized trials. There have not been randomized trials addressing optimal margins of excision or axillary sampling. Whole breast radiation after lumpectomy decreases the risk of recur...
متن کاملDuctal carcinoma in situ (DCIS): raising signposts on an ill-marked treatment path.
JNCI | Editorials 569 Some medical decisions are fairly straightforward. If you break a leg, the recommended treatment is a cast, elevation, and crutches. But if your breast biopsy leads to a diagnosis of ductal carcinoma in situ (DCIS), the treatment path is much less clear. A diagnosis of DCIS brings uncertainty. With the introduction of population-wide screening mammography, radiologists hav...
متن کاملDuctal Carcinoma In Situ Biology, Biomarkers, and Diagnosis
Ductal carcinoma in situ (DCIS) is an often-diagnosed breast disease and a known, non-obligate, precursor to invasive breast carcinoma. In this review, we explore the clinical and pathological features of DCIS, fundamental elements of DCIS biology including gene expression and genetic events, the relationship of DCIS with recurrence and invasive breast cancer, and the interaction of DCIS with t...
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ژورنال
عنوان ژورنال: JNCI Cancer Spectrum
سال: 2018
ISSN: 2515-5091
DOI: 10.1093/jncics/pky063