Epidemiologic evidence for the carcinogenicity of vinyl chloride monomer
نویسندگان
چکیده
منابع مشابه
Carcinogenicity bioassays of vinyl chloride monomer: a model of risk assessment on an experimental basis.
Data are presented regarding the final results of the Bentivoglio (Bologna) project on long-term carcinogenicity bioassays of vinyl chloride (VC). The experimental project studied the effects of the monomer, administered by different routes, concentrations and schedules of treatment, to animals (near 7000) of different species, strains, sex and age. To our knowledge this is the largest experime...
متن کاملResults of sputum, cytology among workers exposed to vinyl chloride monomer and to poly(vinyl chloride).
The results of systematic cytological sputum examinations of 3,380 Italian VC-PVC industry workers and of 2,287 workers in other industries at different potential risk and chosen as control groups are reported. The results indicate an increase in cellular abnormalities and dysplasias in the epithelium of the respiratory tract among VC-PVC workers. These data are in line with experimental result...
متن کاملHealth effects of vinyl chloride monomer: an annotated literature collection.
To assess the relation between oral contraceptive (OC) use and breast cancer, we analysed data from a case-control study conducted in Northern Italy between 1983 and 1991 on 2,309 cases below age 60 and 1,928 controls admitted to hospital for acute diseases unrelated to OC use and to any of the known or potential risk factors for breast cancer.
متن کاملReview of epidemiologic study results of vinyl chloride-related compounds.
Epidemiologic study results addressing the carcinogenicity of six compounds related to vinyl chloride (vinylidene chloride, trichloroethylene, perchloroethylene, carbon tetrachloride, ethylene dibromide and epichlorohydrin) are reviewed. The study results suggest an increased carcinogenic risk among workers exposed to epichlorohydrin and to dry cleaning and degreasing solvents. Although several...
متن کاملUrinary thiodiglycolic acid levels for vinyl chloride monomer-exposed polyvinyl chloride workers.
Thiodiglycolic acid (TdGA) is the major metabolite of vinyl chloride monomer (VCM) detected in human urine. Although urinary TdGA has been reported to be associated with ambient VCM exposure, the relationship between urinary TdGA and a low level of air VCM is not clear. Questionnaires were administered to 16 polyvinyl chloride manufacturing workers to obtain a detailed history of occupation and...
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ژورنال
عنوان ژورنال: Scandinavian Journal of Work, Environment & Health
سال: 2005
ISSN: 0355-3140,1795-990X
DOI: 10.5271/sjweh.875