Epicutaneous immunotherapy: the next step for food allergy desensitization
نویسندگان
چکیده
منابع مشابه
Epicutaneous Immunotherapy for Aeroallergen and Food Allergy
IgE-mediated allergies today affect up to 30 % of the population in industrialized countries. Allergen immunotherapy is the only disease-modifying treatment option with a long-term effect. However, very few patients (<5 %) choose immunotherapy, due to the long treatment duration (between 3-5 years) and possible local and systemic allergic side effects of the allergen administrations. The latter...
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متن کاملEpicutaneous immunotherapy for food allergy as a novel pathway for oral tolerance induction.
Epicutaneous immunotherapy is a developing technique, aiming at desensitizing patients with food allergy with less risks that oral ingestion or injection could generate. Several clinical trials have been performed and are currently running, in milk and peanut allergy, assessing the safety of the technique and its efficacy. Preclinical models indicate a major role in the mechanisms of desensitiz...
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Although the current standard care for patients with food allergy is based on avoidance of the trigger foods with hope of possible gain of tolerance, increasing number of studies have shown that oral immunotherapy is a promising approach. Understanding the transcutaneous sensitization and oral immune tolerance to food antigens has shifted focus of treatment and prevention. However, more studies...
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ژورنال
عنوان ژورنال: Expert Review of Clinical Immunology
سال: 2018
ISSN: 1744-666X,1744-8409
DOI: 10.1080/1744666x.2018.1528873