Epicardium Formation as a Sensor in Toxicology
نویسندگان
چکیده
منابع مشابه
Epicardium Formation as a Sensor in Toxicology
Zebrafish (Danio rerio) are an excellent vertebrate model for studying heart development, regeneration and cardiotoxicity. Zebrafish embryos exposed during the temporal window of epicardium development to the aryl hydrocarbon receptor (AHR) agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exhibit severe heart malformations. TCDD exposure prevents both proepicardial organ (PE) and epicardium d...
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The mature heart may be thought of as consisting of three layers, endocardium, myocardium, and an outer investing tissue called the epicardium. During early formation of the tubular heart of chick embryos, at about the 8-somite stage, two tissue layers become clearly discernible with the light microscope: the endocardium and the developing myocardial wall. The outer epicardial layer does not ap...
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ژورنال
عنوان ژورنال: Journal of Developmental Biology
سال: 2013
ISSN: 2221-3759
DOI: 10.3390/jdb1020112